Peptide–PNA Conjugates: Targeted Transport of Antisense Therapeutics into Tumors
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چکیده
منابع مشابه
Targeted delivery of antisense oligonucleotides by molecular conjugates.
Antisense oligonucleotides efficiently inhibit gene expression in vitro; however, the successful therapeutic application of this technology in vivo will require the development of improved delivery systems. In this report we describe a technique that efficiently delivers antisense oligonucleotides into cells using molecular conjugates. This technique, which was initially developed for the deliv...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2003
ISSN: 1433-7851,1521-3773
DOI: 10.1002/anie.200219978